Precision dosing - is it worth the effort?

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CRE Reduce

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PRO, USA​

Dr Ryan Crass PharmD BCIDP​

Pharmacometrics Group, Ann Arbor, MI​


Dr Ryan Crass is a pharmacometrician with the Ann Arbor Pharmacometrics Group (A2PG). In this role, he works with sponsors of investigational and registered drugs to develop population models quantifying drug pharmacokinetics, as well as, the link between drug exposure and patient clinical efficacy and safety outcomes. His work also includes interpolation and extrapolation through simulation-based analyses to evaluate dosing in specific populations underrepresented in clinical trials. Dr Crass completed his PGY1 and PGY2 Infectious Diseases Pharmacy Residency at the University of Kentucky, as well as, a Clinical Pharmacy Translational Sciences Fellowship with Amit Pai focusing on optimizing the dosing of antimicrobials in specific populations (e.g., obesity, cystic fibrosis, altered renal states).


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CON, Canada​

Dr Sarah Jorgensen PharmD MPH​

Department of Pharmacy, Mount Sinai Hospital, Toronto, ON​


Sarah is an Antimicrobial Stewardship Pharmacist at Mount Sinai Hospital in Toronto, Ontario, Canada. She completed Bachelor of Science degrees in Math and Pharmacy at the University of British Columbia, her PharmD at the University of Florida, Gainesville, FL. She then did a PGY1 Pharmacy Practice residency at Tallahassee Memorial Hospital, Tallahassee, FL, a PGY2 Infectious Disease residency at the University of Southern California, Los Angeles, CA, an Infectious Diseases Pharmacotherapy Research Fellowship at Wayne State University, Detroit, MI, and a Master of Public Health, also at Wayne State University. Sarah’s research has focused on novel treatment strategies for invasive MRSA infections, antimicrobials for multidrug-resistant gram-negative infections, and antimicrobial pharmacokinetics/ pharmacodynamics.

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